Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)
DOI: 10.1016/j.bmcl.2006.12.018
Title: Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3)
Journal Title: Bioorganic & Medicinal Chemistry Letters
Volume: 17
Issue: 5
Publication Date: 1 March 2007
Start Page: 1250
End Page: 1253
Published online: online 9 December 2006
ISSN: 0960-894X
Affiliations:

  • a Procter and Gamble Pharmaceuticals, Health Care Research Center, 8700 Mason-Montgomery Road, Mason, OH 45040, USA

  • b Metastatix, Inc., 1860 Montreal Road, Tucker, GA 30084, USA
  • Abstract: ass of bicyclic pyrrolopyrimidine-based Janus kinase 3 (JAK-3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK-3.
    Accepted: 4 December 2006
    Received: 7 November 2006
    Revised: 2 December 2006
    Tel: +1 404 863 4275.Copyright ©
    Email: mclark@metastatix.com

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