Prevention of oral lesions in children with acute lymphoblastic leukemia
DOI: 10.1016/j.ijporl.2006.04.016
Title: Prevention of oral lesions in children with acute lymphoblastic leukemia
Journal Title: International Journal of Pediatric Otorhinolaryngology
Volume: 70
Issue: 11
Publication Date: November 2006
Start Page: 1847
End Page: 1851
Published online: online 17 August 2006
ISSN: 0165-5876
Author: Leã;o Pereira Pintoa, Lélia Batista de Souzaa, Manuel Antonio Gordó;n-Nú;ñ;eza, Rosilene Calasanz Soaresa, Edja Maria Melo de Brito Costab, Ana Rafaela Luz de Aquinoc, Maria Zé;lia Fernandesd
Affiliations:

  • a Department of Oral Pathology, School of Dentistry, Health Sciences Center, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil

  • b School of Dentistry, Potiguar University (UnP), Natal, RN, Brazil

  • c School of Dentistry, Health Sciences Center, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil

  • d Department of Medicine, School of Medicine, Health Sciences Center, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil
  • Accepted: 25 April 2006
    Received: 16 March 2006
    Revised: 24 April 2006
    Result: Mucositis was observed in six children of group I and eight of group II, and was characterized by erythema, edema and ulcers. Uniform cytologic findings were obtained for the two groups, with a clear predominance of cells of the intermediate layer in all smears, in addition to a perinuclear halo in 18% of the smears.ConclusionThe present results suggest that systematic preventive treatment with 0.12% chlorhexidine gluconate and oral hygiene care reduce the occurrence of oral complications in children with ALL undergoing antineoplastic chemotherapy.
    Tel: +55 84 3215 4138
    Fax: +55 84 3215 4138
    Email: leao@patologiaoral.com.br lppinto@digi.com.br

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