Free triiodothyronine toxicosis in two adolescents
DOI: 10.1016/S0022-3476(94)70319-1
Title: Free triiodothyronine toxicosis in two adolescents
Journal Title: The Journal of Pediatrics
Volume: 124
Issue: 2
Publication Date: February 1994
Start Page: 276鈥?78
End Page: 276鈥?78
Published online: online 27 November 2007
ISSN: 0022-3476
Author: Allen W. Root, MD
Abstract: adolescents had subtle symptoms and signs of thyrotoxicosis but normal levels of total and free thyroxine and total triiodothyronine. Serum concentrations of thyrotropin were undetectable in basal specimens and after administration of thyrotropin-releasing hormone; only free triiodothyronine values were elevated. An increase in serum levels of free triiodothyronine may be the earliest secretory abnormality of an overactive thyroid gland. (J PEDIATR 1994;124:276-8)
Accepted: 16 September 1993
Received: 20 July 1993
Abbreviations: T4, Thyroxine; T3, Triiodothyronine; TBG, Thyroxine-binding globulin; TRH, Thyrotropin-releasing hormone

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